BDBM693356 1-(2-fluorophenyl)-N-(2,3,6-trifluoro-4- ((3-(2-(((3S,5S)-5-fluoro-5- methylpiperidin-3-yl)amino)pyrimidin-4- yl)pyridin-2- yl)oxy)phenyl)methanesulfonamide::US12071425, Compound 275

SMILES C[C@@]1(F)CNC[C@H](C1)Nc1nccc(n1)-c1cccnc1Oc1cc(F)c(NS(=O)(=O)Cc2ccccc2F)c(F)c1F

InChI Key InChIKey=IBSPSZJAMORLKD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 693356   

LigandPNGBDBM693356(1-(2-fluorophenyl)-N-(2,3,6-trifluoro-4- ((3-(2-((...)
Affinity DataIC50: 0.230nMAssay Description:To determine the affinity of compound binding to the kinase domain of IRE1 alpha, a Time Resolved Fluorescence Resonance Energy Transfer (TR-FRET) co...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/6/2024
Entry Details
Go to US Patent