BDBM693327 N-[2-fluoro-3-methyl-4-[[3-[2-[[(3S)-3- piperidyl]amino]pyrimidin-4-yl]-2- pyridyl]oxy]phenyl]-1 phenylmethanesulfonamide::US12071425, Compound 237

SMILES Cc1c(F)c(NS(=O)(=O)Cc2ccccc2)ccc1Oc1ncccc1-c1ccnc(N[C@H]2CCCNC2)n1

InChI Key InChIKey=GYCMERFIKQCCQP-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 693327   

LigandPNGBDBM693327(N-[2-fluoro-3-methyl-4-[[3-[2-[[(3S)-3- piperidyl]...)
Affinity DataIC50: 8.40nMAssay Description:To determine the affinity of compound binding to the kinase domain of IRE1 alpha, a Time Resolved Fluorescence Resonance Energy Transfer (TR-FRET) co...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/6/2024
Entry Details
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LigandPNGBDBM693327(N-[2-fluoro-3-methyl-4-[[3-[2-[[(3S)-3- piperidyl]...)
Affinity DataIC50: 330nMMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
LigandPNGBDBM693327(N-[2-fluoro-3-methyl-4-[[3-[2-[[(3S)-3- piperidyl]...)
Affinity DataIC50: 24nMMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
LigandPNGBDBM693327(N-[2-fluoro-3-methyl-4-[[3-[2-[[(3S)-3- piperidyl]...)
Affinity DataIC50: 1.80nMMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed