BDBM693250 (S)-N-(2,3-difluoro-6-methyl-4-((3-(2- (piperiidn-3-ylamino)pyrimidin-4- yl)pyridin-2-yl)oxy)phenyl)-1- phenylmethanesulfonamide::US12071425, Compound 160

SMILES Cc1cc(Oc2ncccc2-c2ccnc(N[C@H]3CCCNC3)n2)c(F)c(F)c1NS(=O)(=O)Cc1ccccc1

InChI Key InChIKey=QPRFTBDGRCHUGW-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 693250   

LigandPNGBDBM693250((S)-N-(2,3-difluoro-6-methyl-4-((3-(2- (piperiidn-...)
Affinity DataIC50: 5.40nMAssay Description:To determine the affinity of compound binding to the kinase domain of IRE1 alpha, a Time Resolved Fluorescence Resonance Energy Transfer (TR-FRET) co...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/6/2024
Entry Details
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LigandPNGBDBM693250((S)-N-(2,3-difluoro-6-methyl-4-((3-(2- (piperiidn-...)
Affinity DataIC50: 44nMMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
LigandPNGBDBM693250((S)-N-(2,3-difluoro-6-methyl-4-((3-(2- (piperiidn-...)
Affinity DataIC50: 4.5nMMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
LigandPNGBDBM693250((S)-N-(2,3-difluoro-6-methyl-4-((3-(2- (piperiidn-...)
Affinity DataIC50: 0.290nMMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed