BDBM693243 (S)-1-phenyl-N-(2,3,6-trifluoro-4-((3-(2- (piperidin-3-ylamino)pyrimidin-4- yl)pyridin-2- yl)oxy)phenyl)methanesulfonamide::US12071425, Compound 153

SMILES Fc1cc(Oc2ncccc2-c2ccnc(N[C@H]3CCCNC3)n2)c(F)c(F)c1NS(=O)(=O)Cc1ccccc1

InChI Key InChIKey=SRZTYCDVHBJGCJ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 693243   

LigandPNGBDBM693243((S)-1-phenyl-N-(2,3,6-trifluoro-4-((3-(2- (piperid...)
Affinity DataIC50: 3.80nMAssay Description:To determine the affinity of compound binding to the kinase domain of IRE1 alpha, a Time Resolved Fluorescence Resonance Energy Transfer (TR-FRET) co...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/6/2024
Entry Details
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LigandPNGBDBM693243((S)-1-phenyl-N-(2,3,6-trifluoro-4-((3-(2- (piperid...)
Affinity DataIC50: 47nMMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
LigandPNGBDBM693243((S)-1-phenyl-N-(2,3,6-trifluoro-4-((3-(2- (piperid...)
Affinity DataIC50: 4.5nMMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
LigandPNGBDBM693243((S)-1-phenyl-N-(2,3,6-trifluoro-4-((3-(2- (piperid...)
Affinity DataIC50: 3.10nMMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed