BDBM693051 2-(7-((2S,5R)-4-(1-(3,3-dimethyl-2,3-dihydrofuro[3,2-b]pyridin-5-yl)ethyl)-2,5-diethylpiperazin-1-yl)-4-methyl-5-oxo-4,5-dihydro-2H-pyrazolo[4,3-b]pyridin-2-yl)acetonitrile::US20240270751, Compound A352

SMILES CC[C@@H]1CN([C@@H](CC)CN1C(C)c1ccc2OCC(C)(C)c2n1)c1cc(=O)n(C)c2cn(CC#N)nc12

InChI Key InChIKey=SCBGLYFOOVJTNO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 693051   

TargetDiacylglycerol kinase zeta(Human)
Beigene

US Patent
LigandPNGBDBM693051(2-(7-((2S,5R)-4-(1-(3,3-dimethyl-2,3-dihydrofuro[3...)
Affinity DataIC50: 6nMAssay Description:The inhibition activities testing for the compound disclosed herein were carried out at room temperature in assay buffer containing 50 mM HEPES, 10 m...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/3/2024
Entry Details
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TargetDiacylglycerol kinase alpha(Human)
Beigene

US Patent
LigandPNGBDBM693051(2-(7-((2S,5R)-4-(1-(3,3-dimethyl-2,3-dihydrofuro[3...)
Affinity DataIC50: 5.40E+3nMAssay Description:The inhibition activities testing for the compound disclosed herein were carried out at room temperature in assay buffer containing 50 mM HEPES, 10 m...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/3/2024
Entry Details
Go to US Patent