BDBM692494 US20240270735, Compound B69

SMILES FC(F)(F)C(=O)c1cccc(NC(=O)Nc2nnc(s2)-c2ccncc2)c1

InChI Key InChIKey=JONQOCAQOVHFAQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 692494   

TargetCyclin-dependent kinase 19(Human)
Chan Zuckerberg Biohub

US Patent
LigandPNGBDBM692494(US20240270735, Compound B69)
Affinity DataIC50: 10nMAssay Description:The CDK19/CDK8 IC50 values were measured to evaluate activity and to determine CDK19/CDK8 selectivity. The IC50 values of the disclosed compounds was...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/3/2024
Entry Details
Go to US Patent

TargetCyclin-dependent kinase 8(Human)
Chan Zuckerberg Biohub

US Patent
LigandPNGBDBM692494(US20240270735, Compound B69)
Affinity DataIC50: 25nMAssay Description:The CDK19/CDK8 IC50 values were measured to evaluate activity and to determine CDK19/CDK8 selectivity. The IC50 values of the disclosed compounds was...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/3/2024
Entry Details
Go to US Patent