BDBM691986 US20240279215, Compound 447::oxazol-5-ylmethyl (4-((1- (N,N-dimethyl- sulfamoyl)piperidin- 4-yl)methyl)-3- fluorophenyl)carbamate

SMILES CN(C)S(=O)(=O)N1CCC(Cc2ccc(NC(=O)OCc3cnco3)cc2F)CC1

InChI Key InChIKey=KBRCLTGAKQRSJQ-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 691986   

TargetNicotinamide phosphoribosyltransferase(Human)
Cytokinetics, Incorporated

US Patent
LigandPNGBDBM691986(US20240279215, Compound 447 | oxazol-5-ylmethyl (4...)
Affinity DataEC50:  2.31E+3nMAssay Description:Compounds described herein were assayed for their ability to stimulate the synthesis of nicotinamide mononucleotide (NMN) by the enzyme NAMPT. The hu...More data for this Ligand-Target Pair
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Date in BDB:
11/26/2024
Entry Details
US Patent