BDBM691585 4-chlorobenzyl (S)-(4-(1- (3,4-dimethylisoxazole-5- carboxamido)eth- yl)phenyl)carbamate::US20240279215, Compound 46

SMILES C[C@H](NC(=O)c1onc(C)c1C)c1ccc(NC(=O)OCc2ccc(Cl)cc2)cc1

InChI Key InChIKey=YKXSIHKWBJAWPL-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 691585   

TargetNicotinamide phosphoribosyltransferase(Human)
Cytokinetics, Incorporated

US Patent
LigandPNGBDBM691585(US20240279215, Compound 46 | 4-chlorobenzyl (S)-(4...)
Affinity DataEC50:  2.58E+3nMAssay Description:Compounds described herein were assayed for their ability to stimulate the synthesis of nicotinamide mononucleotide (NMN) by the enzyme NAMPT. The hu...More data for this Ligand-Target Pair
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Date in BDB:
11/26/2024
Entry Details
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