BDBM691488 4-carbamoylbenzyl (R)- (4-((2-(pyridin-3- yl)pyrrolidin-1- yl)methyl)phenyl)carbamate::US20240279215, Compound 2

SMILES NC(=O)c1ccc(COC(=O)Nc2ccc(CN3CCC[C@@H]3c3cccnc3)cc2)cc1

InChI Key InChIKey=JNYOROWWFZLELW-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 691488   

TargetNicotinamide phosphoribosyltransferase(Human)
Cytokinetics, Incorporated

US Patent
LigandPNGBDBM691488(US20240279215, Compound 2 | 4-carbamoylbenzyl (R)-...)
Affinity DataEC50:  960nMAssay Description:Compounds described herein were assayed for their ability to stimulate the synthesis of nicotinamide mononucleotide (NMN) by the enzyme NAMPT. The hu...More data for this Ligand-Target Pair
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Date in BDB:
11/26/2024
Entry Details
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