BDBM690596 US12065430, Example 114

SMILES CC(C)N1CC[C@H](C1)n1c(CNc2n[nH]c3cc(Cl)c(cc23)C(C)(C)C)nc(Cl)c1C(=O)NC1CN(C1)C(=O)C=C

InChI Key InChIKey=DWJDNPUYBQAQEB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 690596   

TargetSon of sevenless homolog 1 [564-1049]/GTPase KRas [G12C](Human)
Taiho Pharmaceutical Co.

US Patent
LigandPNGBDBM690596(US12065430, Example 114)
Affinity DataIC50: 7nMAssay Description:The inhibitory activity of compounds on exchange reaction of GDP into GppNHp in Bodipy (trademark) FL-bound KRAS G12C was examined by fluorescence me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
Go to US Patent