BDBM690380 US20240262835, Compound 37

SMILES CN(C1COc2cc(OC(F)F)ccc12)C(=O)c1ccc2nc(N)c3cncn3c2c1

InChI Key InChIKey=QCTVGPCFSUOESX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 690380   

TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Human)
Antengene Discovery

US Patent
LigandPNGBDBM690380(US20240262835, Compound 37)
Affinity DataIC50: 29nMAssay Description:Table 1: The PRMT5 inhibitory activity of test compounds was determined using the MTase-Glo™ assay (Promega), which monitors the product (S-aden...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2024
Entry Details
Go to US Patent