BDBM690355 US20240262835, Compound 12

SMILES CN([C@@H]1COc2cc(ccc12)C(F)(F)F)C(=O)c1ccc2nc(N)c3cncn3c2c1

InChI Key InChIKey=RJCJMTTXIGGZEL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 690355   

TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Human)
Antengene Discovery

US Patent
LigandPNGBDBM690355(US20240262835, Compound 12)
Affinity DataIC50: 26nMAssay Description:Table 1: The PRMT5 inhibitory activity of test compounds was determined using the MTase-Glo™ assay (Promega), which monitors the product (S-aden...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2024
Entry Details
Go to US Patent