BDBM690345 US20240262835, Compound 2

SMILES Cn1ncc(c1-c1c(F)c(Cl)cc(OC2CC2)c1C#N)-c1ccc2c(c1)nc(N)c1cncn21

InChI Key InChIKey=BUGNVQMHLVQZGS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 690345   

TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Human)
Antengene Discovery

US Patent
LigandPNGBDBM690345(US20240262835, Compound 2)
Affinity DataIC50: 45nMAssay Description:Table 1: The PRMT5 inhibitory activity of test compounds was determined using the MTase-Glo™ assay (Promega), which monitors the product (S-aden...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2024
Entry Details
Go to US Patent