BDBM689531 US12054475, Compound 147

SMILES CCc1cnccc1C(=O)Nc1cc2CCC(=O)Nc2c(C)c1C

InChI Key InChIKey=HBMZPJGGZXDXEG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 689531   

TargetRetinal dehydrogenase 2(Human)
Kayothera

US Patent
LigandPNGBDBM689531(US12054475, Compound 147)
Affinity DataIC50: 431nMAssay Description:Recombinant protein extraction: pET-Aldh1a2 transformed BL21-DE3 cultures induced at 20° C. for 19 h with 0.3 mM IPTG rocking. Cultures were spun at ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2024
Entry Details
Go to US Patent

TargetRetinal dehydrogenase 2(Mouse)
Kayothera

US Patent
LigandPNGBDBM689531(US12054475, Compound 147)
Affinity DataIC50: 358nMAssay Description:Recombinant protein extraction: pET-Aldh1a2 transformed BL21-DE3 cultures induced at 20° C. for 19 h with 0.3 mM IPTG rocking. Cultures were spun at ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2024
Entry Details
Go to US Patent