BDBM689517 US12054475, Compound 59

SMILES O=C(Nc1ccc2NC(=O)CCc2c1)c1ccncc1CC1CC1

InChI Key InChIKey=KBPQXBKOFRBWQF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 689517   

TargetRetinal dehydrogenase 2(Human)
Kayothera

US Patent
LigandPNGBDBM689517(US12054475, Compound 59)
Affinity DataIC50: 530nMAssay Description:Recombinant protein extraction: pET-Aldh1a2 transformed BL21-DE3 cultures induced at 20° C. for 19 h with 0.3 mM IPTG rocking. Cultures were spun at ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2024
Entry Details
Go to US Patent

TargetRetinal dehydrogenase 2(Mouse)
Kayothera

US Patent
LigandPNGBDBM689517(US12054475, Compound 59)
Affinity DataIC50: 487nMAssay Description:Recombinant protein extraction: pET-Aldh1a2 transformed BL21-DE3 cultures induced at 20° C. for 19 h with 0.3 mM IPTG rocking. Cultures were spun at ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2024
Entry Details
Go to US Patent