BDBM689461 US12053473, Example I-315

SMILES COCC(=O)N1CCC(CC1)c1cc2c(N[C@H](C)c3cc(N)cc(c3)C(F)(F)F)nc(C)nc2cc1C

InChI Key InChIKey=STEOLKHAZSDTRK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 689461   

TargetSon of sevenless homolog 1(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM689461(US12053473, Example I-315)
Affinity DataIC50: 3nMAssay Description:This assay can be used to examine the potency with which compounds inhibit the protein-protein interaction between SOS1 and KRAS G12D. This demonstra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2024
Entry Details
Go to US Patent