BDBM689395 US12053473, Example I-234

SMILES C[C@@H](Nc1nc(C)nc2ccc(cc12)[C@H]1CC[C@@H](CC1)C(=O)N1CCOCC1)c1cc(N)cc(c1)C(F)(F)F

InChI Key InChIKey=YJWXSDFOGANZBM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 689395   

TargetSon of sevenless homolog 1(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM689395(US12053473, Example I-234)
Affinity DataIC50: 2nMAssay Description:This assay can be used to examine the potency with which compounds inhibit the protein-protein interaction between SOS1 and KRAS G12D. This demonstra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2024
Entry Details
Go to US Patent