BDBM689307 US12053473, Example I-45

SMILES COc1cc2nc(C)nc(N[C@H](C)c3cccc(c3F)C(F)(F)F)c2cc1C1(O)CCN(CC1)C(C)=O

InChI Key InChIKey=DEYRSOVRPZRKLY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 689307   

TargetSon of sevenless homolog 1(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM689307(US12053473, Example I-45)
Affinity DataIC50: 2nMAssay Description:This assay can be used to examine the potency with which compounds inhibit the protein-protein interaction between SOS1 and KRAS G12D. This demonstra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2024
Entry Details
Go to US Patent