BDBM689235 5-((5-chloro-3-(2,2-difluoroethoxy)pyridin- 2-yl)oxy)-3-(2,2-difluoroethyl)-N-(4-methyl- 1,1-dioxidotetrahydro-2H-thiopyran-4-yl)- 3H-imidazo[4,5-b]pyridine-2-carboxamide::US20240254114, Example 54

SMILES CC1(CCS(=O)(=O)CC1)NC(=O)c1nc2ccc(Oc3ncc(Cl)cc3OCC(F)F)nc2n1CC(F)F

InChI Key InChIKey=SURDADQXCZPFHX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 689235   

TargetDiacylglycerol O-acyltransferase 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM689235(US20240254114, Example 54 | 5-((5-chloro-3-(2,2-di...)
Affinity DataIC50: 0.600nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13C18-triolein (13C-1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
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Date in BDB:
11/20/2024
Entry Details
US Patent