BDBM689227 5-[[3-(2,2-difluoroethoxy)-5- fluoro-2-pyridyl]oxy]-N- [(1S,2R)-3,3-difluoro-2- hydroxy-cyclohexyl]-3- methyl-imidazo[4,5- b]pyridine-2-carboxamide::US20240254114, Example 39

SMILES Cn1c(nc2ccc(Oc3ncc(F)cc3OCC(F)F)nc12)C(=O)N[C@H]1CCCC(F)(F)[C@@H]1O

InChI Key InChIKey=JIKXRKXHZXXAPC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 689227   

TargetDiacylglycerol O-acyltransferase 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM689227(US20240254114, Example 39 | 5-[[3-(2,2-difluoroeth...)
Affinity DataIC50: 1.5nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13C18-triolein (13C-1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
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Date in BDB:
11/20/2024
Entry Details
US Patent