BDBM689201 (R) N-(3-(2-(4-(2,3-Dichlorophenyl)-3-methylpiperazin-1-yl)ethyl)cyclobutyl)-2-hydroxy-2-methylpropanamide::US20240254109, Example 22

SMILES C[C@@H]1CN(CCC2CC(C2)NC(=O)C(C)(C)O)CCN1c1cccc(Cl)c1Cl

InChI Key InChIKey=RKMRDVCDQSVRAG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 689201   

TargetD(3) dopamine receptor(Human)
Shanghai Hansoh Biomedical

US Patent
LigandPNGBDBM689201(US20240254109, Example 22 | (R) N-(3-(2-(4-(2,3-Di...)
Affinity DataIC50: 2.78nMAssay Description:Dopamine D3 Receptor: Experimental buffer: 50 mM Tris-HCl pH 7.4, 10 mm MgCl2; washing liquor: 50 mM Tris-HCl pH 7.4, stored at 4° C.; 0.5% PEI solut...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2024
Entry Details
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Target5-hydroxytryptamine receptor 2A(Human)
Shanghai Hansoh Biomedical

US Patent
LigandPNGBDBM689201(US20240254109, Example 22 | (R) N-(3-(2-(4-(2,3-Di...)
Affinity DataIC50: 9.63nMAssay Description:5-HT2A Receptor: Experimental buffer: 50 mM Tris-HCl pH 7.4, 4 mM CaCl2); washing liquor: 50 mM Tris-HCl pH 7.4, stored at 4° C.; 0.5% PEI solution: ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2024
Entry Details
Go to US Patent