BDBM689197 N-(Trans-3-(2-(4-(2,3-dichlorophenyl)piperazin-1-yl)ethyl)cyclobutyl)isoxazole-3-carboxamide::US20240254109, Example 17A

SMILES Clc1cccc(N2CCN(CC[C@H]3C[C@@H](C3)NC(=O)c3ccon3)CC2)c1Cl

InChI Key InChIKey=JKQLCOBZNOKACE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 689197   

TargetD(3) dopamine receptor(Human)
Shanghai Hansoh Biomedical

US Patent
LigandPNGBDBM689197(US20240254109, Example 17A | N-(Trans-3-(2-(4-(2,3...)
Affinity DataIC50: 0.300nMAssay Description:Dopamine D3 Receptor: Experimental buffer: 50 mM Tris-HCl pH 7.4, 10 mm MgCl2; washing liquor: 50 mM Tris-HCl pH 7.4, stored at 4° C.; 0.5% PEI solut...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2024
Entry Details
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Target5-hydroxytryptamine receptor 2A(Human)
Shanghai Hansoh Biomedical

US Patent
LigandPNGBDBM689197(US20240254109, Example 17A | N-(Trans-3-(2-(4-(2,3...)
Affinity DataIC50: 1.92nMAssay Description:5-HT2A Receptor: Experimental buffer: 50 mM Tris-HCl pH 7.4, 4 mM CaCl2); washing liquor: 50 mM Tris-HCl pH 7.4, stored at 4° C.; 0.5% PEI solution: ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2024
Entry Details
Go to US Patent