BDBM689191 US20240254109, Example 12A::US20240254109, Example 12B

SMILES Clc1cccc(N2CCN(CCC3CC(C3)NC(=O)c3ncco3)CC2)c1Cl

InChI Key InChIKey=VSYIBUZNSGDCAN-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 689191   

TargetD(3) dopamine receptor(Human)
Shanghai Hansoh Biomedical

US Patent
LigandPNGBDBM689191(US20240254109, Example 12B | US20240254109, Exampl...)
Affinity DataIC50: 0.370nMAssay Description:Dopamine D3 Receptor: Experimental buffer: 50 mM Tris-HCl pH 7.4, 10 mm MgCl2; washing liquor: 50 mM Tris-HCl pH 7.4, stored at 4° C.; 0.5% PEI solut...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2024
Entry Details
Go to US Patent

TargetD(3) dopamine receptor(Human)
Shanghai Hansoh Biomedical

US Patent
LigandPNGBDBM689191(US20240254109, Example 12B | US20240254109, Exampl...)
Affinity DataIC50: 2.54nMAssay Description:Dopamine D3 Receptor: Experimental buffer: 50 mM Tris-HCl pH 7.4, 10 mm MgCl2; washing liquor: 50 mM Tris-HCl pH 7.4, stored at 4° C.; 0.5% PEI solut...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2024
Entry Details
Go to US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Shanghai Hansoh Biomedical

US Patent
LigandPNGBDBM689191(US20240254109, Example 12B | US20240254109, Exampl...)
Affinity DataIC50: 4.19nMAssay Description:5-HT2A Receptor: Experimental buffer: 50 mM Tris-HCl pH 7.4, 4 mM CaCl2); washing liquor: 50 mM Tris-HCl pH 7.4, stored at 4° C.; 0.5% PEI solution: ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2024
Entry Details
Go to US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Shanghai Hansoh Biomedical

US Patent
LigandPNGBDBM689191(US20240254109, Example 12B | US20240254109, Exampl...)
Affinity DataIC50: 8.73nMAssay Description:5-HT2A Receptor: Experimental buffer: 50 mM Tris-HCl pH 7.4, 4 mM CaCl2); washing liquor: 50 mM Tris-HCl pH 7.4, stored at 4° C.; 0.5% PEI solution: ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2024
Entry Details
Go to US Patent