BDBM688919 (R)-10-methyl-3-(6-(3-morpholinoprop-1-en-2-yl)pyrimidin-4-yl)-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-139

SMILES C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2cc(ncn2)C(=C)CN2CCOCC2)C(=O)N1

InChI Key InChIKey=MGRAOTDXRNYSHM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 688919   

TargetMAP kinase-activated protein kinase 2(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM688919(US20240190890, Compound I-139 | (R)-10-methyl-3-(6...)
Affinity DataIC50: 2nMAssay Description:Briefly, 10× stock solutions of MK2 (PV3317, from Life Technologies), 1.13X ATP (AS001A), and Sox conjugated peptide substrate, S/T3-Sox, (KZN1031) w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
Go to US Patent

TargetMAP kinase-activated protein kinase 2(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM688919(US20240190890, Compound I-139 | (R)-10-methyl-3-(6...)
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed