BDBM688620 US20240190854, Example 116

SMILES N[C@@H](Cc1cccc(n1)C#N)c1ccccc1-c1noc2ccccc12

InChI Key InChIKey=WGZDWYPYSFXFKW-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 688620   

LigandPNGBDBM688620(US20240190854, Example 116)
Affinity DataIC50: 700nMAssay Description:PatchXpress 7000A Solutions are used to record HCN currents.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
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LigandPNGBDBM688620(US20240190854, Example 116)
Affinity DataIC50: 1.35E+4nMAssay Description:PatchXpress 7000A Solutions are used to record HCN currents.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
Go to US Patent

LigandPNGBDBM688620(US20240190854, Example 116)
Affinity DataIC50: 3.40E+3nMAssay Description:PatchXpress 7000A Solutions are used to record HCN currents.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
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TargetPotassium voltage-gated channel subfamily H member 2(Human)
King''s College London

US Patent
LigandPNGBDBM688620(US20240190854, Example 116)
Affinity DataIC50: 1.03E+4nMAssay Description:IonWorks Quattro Solutions are used to record hERG and nav1.5 currents.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
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TargetSodium channel protein type 5 subunit alpha(Human)
King''s College London

US Patent
LigandPNGBDBM688620(US20240190854, Example 116)
Affinity DataIC50: 1.11E+4nMAssay Description:IonWorks Quattro Solutions are used to record hERG and nav1.5 currents.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
Go to US Patent