BDBM688576 US20240190854, Example 71

SMILES N[C@@H](Cc1nc(ccc1F)C#N)c1ccccc1-c1noc2ccccc12

InChI Key InChIKey=BIFSIVXPCUJYPO-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 688576   

LigandPNGBDBM688576(US20240190854, Example 71)
Affinity DataIC50: 500nMAssay Description:PatchXpress 7000A Solutions are used to record HCN currents.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
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LigandPNGBDBM688576(US20240190854, Example 71)
Affinity DataIC50: 3.50E+3nMAssay Description:PatchXpress 7000A Solutions are used to record HCN currents.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
Go to US Patent

LigandPNGBDBM688576(US20240190854, Example 71)
Affinity DataIC50: 4.40E+3nMAssay Description:PatchXpress 7000A Solutions are used to record HCN currents.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
Go to US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
King''s College London

US Patent
LigandPNGBDBM688576(US20240190854, Example 71)
Affinity DataIC50: 9.70E+3nMAssay Description:IonWorks Quattro Solutions are used to record hERG and nav1.5 currents.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
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TargetSodium channel protein type 5 subunit alpha(Human)
King''s College London

US Patent
LigandPNGBDBM688576(US20240190854, Example 71)
Affinity DataIC50: 2.26E+4nMAssay Description:IonWorks Quattro Solutions are used to record hERG and nav1.5 currents.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
Go to US Patent