BDBM688502 N-(3-(4-methyl-1H- imidazol-1-yl)-5- (trifluoromethyl)phenyl)- 1-((2-(methylcarbamoyl) pyridin- 4-yl)methyl)indoline- 6-carboxamide::US20240190847, Example 2

SMILES CNC(=O)c1cc(CN2CCc3ccc(cc23)C(=O)Nc2cc(cc(c2)C(F)(F)F)-n2cnc(C)c2)ccn1

InChI Key InChIKey=YCHDBTDZZBEBPC-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 688502   

TargetEpithelial discoidin domain-containing receptor 1(Human)
Chiesi Farmaceutici

US Patent
LigandPNGBDBM688502(US20240190847, Example 2 | N-(3-(4-methyl-1H- imid...)
Affinity DataIC50: 37.5nMAssay Description:DDR1 and DDR2 binding assays were performed using Life Technologies LanthaScreen Europium Kinase Binding assay. The compounds were incubated with 5 n...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
Go to US Patent

TargetEpithelial discoidin domain-containing receptor 1(Human)
Chiesi Farmaceutici

US Patent
LigandPNGBDBM688502(US20240190847, Example 2 | N-(3-(4-methyl-1H- imid...)
Affinity DataKi: <10nMAssay Description:DDR1 and DDR2 binding assays were performed using Life Technologies LanthaScreen Europium Kinase Binding assay. The compounds were incubated with 5 n...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
Go to US Patent

TargetDiscoidin domain-containing receptor 2(Human)
Chiesi Farmaceutici

US Patent
LigandPNGBDBM688502(US20240190847, Example 2 | N-(3-(4-methyl-1H- imid...)
Affinity DataKi: <10nMAssay Description:DDR1 and DDR2 binding assays were performed using Life Technologies LanthaScreen Europium Kinase Binding assay. The compounds were incubated with 5 n...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
Go to US Patent