BDBM688493 US20240190824, Compound 92::tert-butyl (4-chloro-3-((3-fluoro-5-(1- (4-fluorophenyl)-1H-pyrazol-4 yl)pyridin-2- yl)carbamoyl)phenyl)carbamate

SMILES CC(C)(C)OC(=O)Nc1ccc(Cl)c(c1)C(=O)Nc1ncc(cc1F)-c1cnn(c1)-c1ccc(F)cc1

InChI Key InChIKey=ITGJMSFFZTZRKI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 688493   

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Ono Pharmaceutical Co.

US Patent
LigandPNGBDBM688493(US20240190824, Compound 92 | tert-butyl (4-chloro-...)
Affinity DataIC50: 130nMAssay Description:TBDCHO-K1 cells stably expressing human TREK-1 or HEK293 cells stably expressing human TREK-2 are plated in 384-well plates, cultured overnight, load...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
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