BDBM688491 US20240190824, Compound 90::tert-butyl (3-((6-(benzyloxy)-2- methylpyridin-3-yl)carbamoyl)-4- chlorophenyl)carbamate

SMILES Cc1nc(OCc2ccccc2)ccc1NC(=O)c1cc(NC(=O)OC(C)(C)C)ccc1Cl

InChI Key InChIKey=PGYPWBGMNPUBID-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 688491   

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Ono Pharmaceutical Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 688491BDBM688491(US20240190824, Compound 90 | tert-butyl (3-((6-(be...)
Affinity DataIC50: 850nMAssay Description:TBDCHO-K1 cells stably expressing human TREK-1 or HEK293 cells stably expressing human TREK-2 are plated in 384-well plates, cultured overnight, load...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
US Patent

TargetPotassium channel subfamily K member 2(Human)
Ono Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 688491BDBM688491(US20240190824, Compound 90 | tert-butyl (3-((6-(be...)
Affinity DataIC50: 850nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed