BDBM688490 4-amino-N-(4-(benzyloxy)-2- methylphenyl)-2-chlorobenzamide::US20240190824, Compound 89

SMILES Cc1cc(OCc2ccccc2)ccc1NC(=O)c1ccc(N)cc1Cl

InChI Key InChIKey=XWYVBRKNCYRBRQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 688490   

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Ono Pharmaceutical Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 688490BDBM688490(US20240190824, Compound 89 | 4-amino-N-(4-(benzylo...)
Affinity DataIC50: 7.67E+3nMAssay Description:TBDCHO-K1 cells stably expressing human TREK-1 or HEK293 cells stably expressing human TREK-2 are plated in 384-well plates, cultured overnight, load...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
US Patent

TargetPotassium channel subfamily K member 2(Human)
Ono Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 688490BDBM688490(US20240190824, Compound 89 | 4-amino-N-(4-(benzylo...)
Affinity DataIC50: 7.70E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed