BDBM688488 US20240190824, Compound 87::tert-butyl N-[3-[(5-benzyloxy-3- methyl-2-pyridyl)carbamoyl]-4- chloro-phenyl]carbamate

SMILES Cc1cc(OCc2ccccc2)cnc1NC(=O)c1cc(NC(=O)OC(C)(C)C)ccc1Cl

InChI Key InChIKey=MSAGLSLZPFYWPK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 688488   

TargetPotassium channel subfamily K member 2(Human)
Ono Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 688488BDBM688488(US20240190824, Compound 87 | tert-butyl N-[3-[(5-b...)
Affinity DataIC50: 560nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Ono Pharmaceutical Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 688488BDBM688488(US20240190824, Compound 87 | tert-butyl N-[3-[(5-b...)
Affinity DataIC50: 560nMAssay Description:TBDCHO-K1 cells stably expressing human TREK-1 or HEK293 cells stably expressing human TREK-2 are plated in 384-well plates, cultured overnight, load...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
US Patent