BDBM688461 2-chloro-5-(3,3-dimethylazetidine-1- carbonyl)-N-[3-methyl-5-(2- phenylethynyl)-2-pyridyl]benzamide::US20240190824, Compound 60

SMILES Cc1cc(cnc1NC(=O)c1cc(ccc1Cl)C(=O)N1CC(C)(C)C1)C#Cc1ccccc1

InChI Key InChIKey=ARQBSMIHDMBLIR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 688461   

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Ono Pharmaceutical Co.

US Patent
LigandPNGBDBM688461(US20240190824, Compound 60 | 2-chloro-5-(3,3-dimet...)
Affinity DataIC50: 140nMAssay Description:TBDCHO-K1 cells stably expressing human TREK-1 or HEK293 cells stably expressing human TREK-2 are plated in 384-well plates, cultured overnight, load...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
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