BDBM688438 US20240190824, Compound 37::tert-butyl N-[4-chloro-3-[[3-chloro-5- (2-phenylethynyl)-2- pyridyl]carbamoyl]phenyl]carbamate

SMILES CC(C)(C)OC(=O)Nc1ccc(Cl)c(c1)C(=O)Nc1ncc(cc1Cl)C#Cc1ccccc1

InChI Key InChIKey=FHQPBUMIVPHREO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 688438   

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Ono Pharmaceutical Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 688438BDBM688438(US20240190824, Compound 37 | tert-butyl N-[4-chlor...)
Affinity DataIC50: 430nMAssay Description:TBDCHO-K1 cells stably expressing human TREK-1 or HEK293 cells stably expressing human TREK-2 are plated in 384-well plates, cultured overnight, load...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
US Patent

TargetPotassium channel subfamily K member 2(Human)
Ono Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 688438BDBM688438(US20240190824, Compound 37 | tert-butyl N-[4-chlor...)
Affinity DataIC50: 430nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed