BDBM688428 2-chloro-5-[[(1S,2S)-2- methylcyclopropanecarbonyl]amino]- N-[3-methyl-5-(2-phenylethynyl)-2- pyridyl]benzamide::US20240190824, Compound 27

SMILES C[C@H]1C[C@@H]1C(=O)Nc1ccc(Cl)c(c1)C(=O)Nc1ncc(cc1C)C#Cc1ccccc1

InChI Key InChIKey=HVKQHCYZILHTGS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 688428   

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Ono Pharmaceutical Co.

US Patent
LigandPNGBDBM688428(US20240190824, Compound 27 | 2-chloro-5-[[(1S,2S)-...)
Affinity DataIC50: 100nMAssay Description:TBDCHO-K1 cells stably expressing human TREK-1 or HEK293 cells stably expressing human TREK-2 are plated in 384-well plates, cultured overnight, load...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
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