BDBM688427 US20240190824, Compound 26::tert-butyl (4-chloro-3-((2-methyl-4- (phenoxymethyl)phenyl)carbamoyl) phenyl)carbamate

SMILES Cc1cc(COc2ccccc2)ccc1NC(=O)c1cc(NC(=O)OC(C)(C)C)ccc1Cl

InChI Key InChIKey=IBRYBTCSHFOGSD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 688427   

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Ono Pharmaceutical Co.

US Patent
LigandPNGBDBM688427(US20240190824, Compound 26 | tert-butyl (4-chloro-...)
Affinity DataIC50: 670nMAssay Description:TBDCHO-K1 cells stably expressing human TREK-1 or HEK293 cells stably expressing human TREK-2 are plated in 384-well plates, cultured overnight, load...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
Go to US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Ono Pharmaceutical Co.

US Patent
LigandPNGBDBM688427(US20240190824, Compound 26 | tert-butyl (4-chloro-...)
Affinity DataIC50: 122nMAssay Description:TBDCHO-K1 cells stably expressing human TREK-1 or HEK293 cells stably expressing human TREK-2 are plated on glass coverslips, and voltage clamped in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
Go to US Patent