BDBM688419 2-chloro-N-[5-[2-(3- fluorophenyl)ethynyl]-3-methyl-2- pyridyl]-5-(3-hydroxy-3-methyl- azetidine-1-carbonyl)benzamide::US20240190824, Compound 18

SMILES Cc1cc(cnc1NC(=O)c1cc(ccc1Cl)C(=O)N1CC(C)(O)C1)C#Cc1cccc(F)c1

InChI Key InChIKey=XCWPGKVTZQSLBZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 688419   

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Ono Pharmaceutical Co.

US Patent
LigandPNGBDBM688419(US20240190824, Compound 18 | 2-chloro-N-[5-[2-(3- ...)
Affinity DataIC50: 240nMAssay Description:TBDCHO-K1 cells stably expressing human TREK-1 or HEK293 cells stably expressing human TREK-2 are plated in 384-well plates, cultured overnight, load...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
Go to US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Ono Pharmaceutical Co.

US Patent
LigandPNGBDBM688419(US20240190824, Compound 18 | 2-chloro-N-[5-[2-(3- ...)
Affinity DataIC50: 86nMAssay Description:TBDCHO-K1 cells stably expressing human TREK-1 or HEK293 cells stably expressing human TREK-2 are plated on glass coverslips, and voltage clamped in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
Go to US Patent