BDBM688414 N-[4-chloro-3-[[5-[2-(3- fluorophenyl)ethynyl]-3-methyl-2- pyridyl]carbamoyl]phenyl]-1,4- dioxane-2-carboxamide::US20240190824, Compound 13

SMILES Cc1cc(cnc1NC(=O)c1cc(NC(=O)C2COCCO2)ccc1Cl)C#Cc1cccc(F)c1

InChI Key InChIKey=BJINHKIDRPBEJO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 688414   

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Ono Pharmaceutical Co.

US Patent
LigandPNGBDBM688414(US20240190824, Compound 13 | N-[4-chloro-3-[[5-[2-...)
Affinity DataIC50: 280nMAssay Description:TBDCHO-K1 cells stably expressing human TREK-1 or HEK293 cells stably expressing human TREK-2 are plated in 384-well plates, cultured overnight, load...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
Go to US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Ono Pharmaceutical Co.

US Patent
LigandPNGBDBM688414(US20240190824, Compound 13 | N-[4-chloro-3-[[5-[2-...)
Affinity DataIC50: 68nMAssay Description:TBDCHO-K1 cells stably expressing human TREK-1 or HEK293 cells stably expressing human TREK-2 are plated on glass coverslips, and voltage clamped in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
Go to US Patent