BDBM688363 US20240189315, Example 11

SMILES C[C@H]1CN2CC[C@]1(F)c1cc(Cl)cnc1O[C@H]1C[C@H](N(C1)c1nc(COC(=O)CCC2=O)nc2c1oc1ccccc21)C(O)=O

InChI Key InChIKey=VAELQRNGIBXLFY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 688363   

TargetCyclic GMP-AMP synthase(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM688363(US20240189315, Example 11)
Affinity DataIC50: 2.80nMAssay Description:in vitro human biochemical cGAS inhibition.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
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