BDBM687883 US20240246984, Compound 30.

SMILES Fc1cccc(F)c1-c1nc(Nc2ccc(cc2)C(=O)N2CCNCC2)c2n1cc[nH]c2=O

InChI Key InChIKey=QYJHZOLXCAAEGZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 687883   

TargetTyrosine-protein kinase JAK2(Human)
Beijing Innocare Pharma Tech Co.

US Patent
LigandPNGBDBM687883(US20240246984, Compound 30.)
Affinity DataIC50: 0.800nMAssay Description:The enzymatic activity of JAK2 was assessed by detecting the substrate phosphorylation level in a kinase reaction with a homogeneous time-resolved fl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
Go to US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Beijing Innocare Pharma Tech Co.

US Patent
LigandPNGBDBM687883(US20240246984, Compound 30.)
Affinity DataIC50: 0.100nMAssay Description:The enzymatic activity of TYK2 was assessed by detecting the substrate phosphorylation level in a kinase reaction with a homogeneous time-resolved fl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
Go to US Patent