BDBM687881 US20240246984, Compound 28.

SMILES NC(=O)c1ccc(Nc2nc(-c3c(F)cccc3Cl)n3cc[nH]c(=O)c23)cc1

InChI Key InChIKey=GTPHOMRIDNXGGJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 687881   

TargetTyrosine-protein kinase JAK2(Human)
Beijing Innocare Pharma Tech Co.

US Patent
LigandPNGBDBM687881(US20240246984, Compound 28.)
Affinity DataIC50: 0.600nMAssay Description:The enzymatic activity of JAK2 was assessed by detecting the substrate phosphorylation level in a kinase reaction with a homogeneous time-resolved fl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
Go to US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Beijing Innocare Pharma Tech Co.

US Patent
LigandPNGBDBM687881(US20240246984, Compound 28.)
Affinity DataIC50: 0.0300nMAssay Description:The enzymatic activity of TYK2 was assessed by detecting the substrate phosphorylation level in a kinase reaction with a homogeneous time-resolved fl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
Go to US Patent