BDBM687879 US20240246984, Compound 26.

SMILES Cn1cc(Nc2nc(-c3c(F)cccc3Cl)n3cc[nH]c(=O)c23)cn1

InChI Key InChIKey=MFANTCFRQWVMFZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 687879   

TargetTyrosine-protein kinase JAK2(Human)
Beijing Innocare Pharma Tech Co.

US Patent
LigandPNGBDBM687879(US20240246984, Compound 26.)
Affinity DataIC50: 2.90nMAssay Description:The enzymatic activity of JAK2 was assessed by detecting the substrate phosphorylation level in a kinase reaction with a homogeneous time-resolved fl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
Go to US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Beijing Innocare Pharma Tech Co.

US Patent
LigandPNGBDBM687879(US20240246984, Compound 26.)
Affinity DataIC50: 0.700nMAssay Description:The enzymatic activity of TYK2 was assessed by detecting the substrate phosphorylation level in a kinase reaction with a homogeneous time-resolved fl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
Go to US Patent