BDBM687823 US20240246981, Example 51

SMILES Cc1cc(C)n(n1)-c1cncc(c1)-c1cccc(C#N)c1N1CCC(CC1)c1nncn1C

InChI Key InChIKey=VADKUPKHFKORNV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 687823   

TargetGlutaminyl-peptide cyclotransferase-like protein(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM687823(US20240246981, Example 51)
Affinity DataIC50: 2nMAssay Description:QPCT or QPCTL dependent conversion of N-terminal glutamine to pyroglutamate of CD47 was monitored via MALDI-TOF MS. Test compounds were dissolved in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
Go to US Patent

TargetGlutaminyl-peptide cyclotransferase(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM687823(US20240246981, Example 51)
Affinity DataIC50: 8nMAssay Description:QPCT or QPCTL dependent conversion of N-terminal glutamine to pyroglutamate of CD47 was monitored via MALDI-TOF MS. Test compounds were dissolved in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
Go to US Patent