BDBM687777 US20240246984, Compound 15.::US20240246984, Compound 2.

SMILES Fc1cccc(F)c1-c1nc(Nc2ccc(cc2)C(=O)N2CCOCC2)c2C(=O)NCCn12

InChI Key InChIKey=XIZMNLZDSOAQFL-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 687777   

TargetTyrosine-protein kinase JAK2(Human)
Beijing Innocare Pharma Tech Co.

US Patent
LigandPNGBDBM687777(US20240246984, Compound 2. | US20240246984, Compou...)
Affinity DataIC50: 1.90nMAssay Description:The enzymatic activity of JAK2 was assessed by detecting the substrate phosphorylation level in a kinase reaction with a homogeneous time-resolved fl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
Go to US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Beijing Innocare Pharma Tech Co.

US Patent
LigandPNGBDBM687777(US20240246984, Compound 2. | US20240246984, Compou...)
Affinity DataIC50: 0.200nMAssay Description:The enzymatic activity of TYK2 was assessed by detecting the substrate phosphorylation level in a kinase reaction with a homogeneous time-resolved fl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK2(Human)
Beijing Innocare Pharma Tech Co.

US Patent
LigandPNGBDBM687777(US20240246984, Compound 2. | US20240246984, Compou...)
Affinity DataIC50: 1.30nMAssay Description:The enzymatic activity of JAK2 was assessed by detecting the substrate phosphorylation level in a kinase reaction with a homogeneous time-resolved fl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
Go to US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Beijing Innocare Pharma Tech Co.

US Patent
LigandPNGBDBM687777(US20240246984, Compound 2. | US20240246984, Compou...)
Affinity DataIC50: 0.200nMAssay Description:The enzymatic activity of TYK2 was assessed by detecting the substrate phosphorylation level in a kinase reaction with a homogeneous time-resolved fl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
Go to US Patent