BDBM687656 US20240246964, Compound 677

SMILES COc1cc(ccc1CN1CC2(C1)CN(C2)C(C)=O)-c1nccc(c1Cl)-c1cccc(NC(=O)c2ccc(CN3CC4(C3)CN(C4)C(C)=O)cn2)c1Cl

InChI Key InChIKey=IPKCTQGWAZNBJH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 687656   

TargetProgrammed cell death 1 ligand 1(Human)
Arbutus Biopharma

US Patent
LigandPNGBDBM687656(US20240246964, Compound 677)
Affinity DataIC50: 0.0400nMAssay Description:PD-L1 His protein was prepared and added at the final concentration of 6 nM in the White opaque 384 well plate (Corning cat #3824BC). PD-L1 small mol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
Go to US Patent