BDBM687633 US20240246964, Compound 654

SMILES COc1cc(cn2nc(CNCCO)nc12)-c1nccc(c1Cl)-c1cccc(c1Cl)-c1ccc(CNC2CCN(CC2)C(C)=O)c(OC)n1

InChI Key InChIKey=JZHVBCAMQJFOJB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 687633   

TargetProgrammed cell death 1 ligand 1(Human)
Arbutus Biopharma

US Patent
LigandPNGBDBM687633(US20240246964, Compound 654)
Affinity DataIC50: 0.0700nMAssay Description:PD-L1 His protein was prepared and added at the final concentration of 6 nM in the White opaque 384 well plate (Corning cat #3824BC). PD-L1 small mol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
Go to US Patent