BDBM687571 US20240246964, Compound 592

SMILES COc1cc(ccc1CN[C@@H]1C[C@H](O)C1)-c1ncnc(c1Cl)-c1cccc(c1Cl)-c1ccc(CN[C@@H]2C[C@H](O)C2)c(OC)n1

InChI Key InChIKey=VIFVJFRMFIQHEA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 687571   

TargetProgrammed cell death 1 ligand 1(Human)
Arbutus Biopharma

US Patent
LigandPNGBDBM687571(US20240246964, Compound 592)
Affinity DataIC50: 0.0900nMAssay Description:PD-L1 His protein was prepared and added at the final concentration of 6 nM in the White opaque 384 well plate (Corning cat #3824BC). PD-L1 small mol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
Go to US Patent