BDBM686601 US20240246937, Example 47

SMILES O=c1n(Cc2nnc(s2)-c2ccccc2)ccn([C@H]2C[C@@H](C2)c2ccccc2)c1=O

InChI Key InChIKey=IHHMHHGKHLQZHP-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 686601   

TargetInterleukin-1 receptor antagonist protein(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM686601(US20240246937, Example 47)
Affinity DataEC50:  3nMAssay Description:Using this assay, the potency (EC50) of each compound was determined from a ten-point (1:3 serial dilution) titration curve using the following outli...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
Go to US Patent