BDBM686599 US20240246937, Example 45

SMILES Fc1ccccc1-c1nnc(Cn2ccn([C@@H]3C[C@@H]4C[C@@H]4C3)c(=O)c2=O)s1

InChI Key InChIKey=WPEMVKMQOKDNOO-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 686599   

TargetInterleukin-1 receptor antagonist protein(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM686599(US20240246937, Example 45)
Affinity DataEC50:  5nMAssay Description:Using this assay, the potency (EC50) of each compound was determined from a ten-point (1:3 serial dilution) titration curve using the following outli...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
Go to US Patent