BDBM686594 US20240246937, Example 40::US20240246937, Example 41

SMILES Fc1ccc(cc1)-c1nnc(Cn2ccn([C@@H]3C[C@@H]4C[C@@H]4C3)c(=O)c2=O)s1

InChI Key InChIKey=CRJSXFUKJYTGNI-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 686594   

TargetInterleukin-1 receptor antagonist protein(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM686594(US20240246937, Example 41 | US20240246937, Example...)
Affinity DataEC50:  4nMAssay Description:Using this assay, the potency (EC50) of each compound was determined from a ten-point (1:3 serial dilution) titration curve using the following outli...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
Go to US Patent

TargetInterleukin-1 receptor antagonist protein(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM686594(US20240246937, Example 41 | US20240246937, Example...)
Affinity DataEC50:  2nMAssay Description:Using this assay, the potency (EC50) of each compound was determined from a ten-point (1:3 serial dilution) titration curve using the following outli...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
Go to US Patent