BDBM686259 US20240245694, Example 22B

SMILES CC(=O)N1CCN(CC1)c1c2CC[C@@H](C(=O)Nc3ccc(cc3)C(F)(F)F)n2c2nc(nn2c1=O)-c1ccccc1

InChI Key InChIKey=NMIYQSUKIKGCHA-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 686259   

TargetBifunctional 3'-5' exonuclease/ATP-dependent helicase WRN [517-1238](Human)
Novartis

US Patent

LigandBDBM686259(US20240245694, Example 22B)Copy SMILESCopy InChI

Affinity DataIC50: 1.00E+5nMAssay Description:The core helicase motif of the WRN protein (aa N517-P1238) was produced for this assay (protein production as described above). A 45 oligonucleotide ...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
11/7/2024
Entry Details
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